Creating the Mac and Cheese Meatloaf Casserole is simple. Follow these easy steps to assemble this delightful dish:

1. Preheat the Oven: Preheat your oven to 350°F (175°C).
2. Cook the Macaroni: In a pot, cook the elbow macaroni according to package instructions. Drain and set aside.
3. Prepare the Meatloaf Mixture: In a large bowl, combine ground beef, breadcrumbs, cheddar cheese, eggs, garlic powder, onion powder, salt, and black pepper. Mix until well combined.
4. Add the Soup and Milk: Incorporate the cheddar cheese soup and milk into the meat mixture. Ensure everything is well blended.
5. Combine Macaroni and Meat Mixture: Gently fold the cooked macaroni into the meatloaf mixture until evenly distributed.
6. Transfer to Baking Dish: Pour the combined mixture into a greased baking dish, smoothing the top with a spatula.
7. Spread Ketchup on Top: Evenly spread ketchup over the top of the casserole. This adds flavor and creates a beautiful glaze.
8. Bake: Place the casserole in the preheated oven and bake for 45 minutes, or until the meatloaf is cooked through and the top is golden brown.
9. Cool Slightly: Remove from the oven and let it cool for about 10 minutes before serving. This allows the ingredients to set slightly.
10. Garnish and Serve: Optionally, sprinkle with fresh parsley for a touch of color before serving.

This step-by-step guide will help you create an amazing Mac and Cheese Meatloaf Casserole without any stress or hassle.